History of Kambo
The Legend and History of Kambo Treatment
About Kambo
Kambo is a secretion from the Giant Green Monkey Tree Frog, known in science as the Phyllomedusa Bicolor. The secretion is not a poison because it alone is NOT capable of causing illness, injury, or death.
In the Amazon, it is regarded as a medicine; however, this should not be confused with the Western definition of pharmaceutical medicine.
Those of us who give Kambo are practitioners, not doctors.
The Kambo frog has no natural predators & is found in abundance across the Upper Amazon rainforest areas of Bolivia, Brazil, Colombia, Peru, French Guiana, Suriname & Venezuela. The only known real threat to this frog species is the potential destruction of their habitat. These giant frogs reach up to 12cm in length and reproduce prolifically throughout the year - mainly from Nov-May. They construct hanging nests from folded leaves 1-3 meters above ponds and streams. The females deposit a mass of eggs into these nests. A single spawn contains a thousand eggs on average from which tadpoles emerge within 11-14 days.
No one is 100% certain the catalyst for producing the secretion is, but it is widely believed to be sequestered from their diet.
The frogs do not produce their secretion when they are removed from their natural environment.
Neuro and Bio-Active Peptides in Kambo
Dermorphin - Dermorphin has an opiate-like effect on mu-opioid receptors, making it a very potent painkiller with effects 30-40 times stronger than morphine.
Deltorphin - Deltorphin is also a powerful painkiller and delta opioid agonist.
Phyllomedusin - A neuropeptide (possible to link to Wikipedia page on neuropeptides?) that has a powerful effect on intestines and bowels, contributing to the purging often experienced when taking kambo.
Phyllokinin - This neuropeptide can cause a long-lasting reduction in blood pressure.
Phyllocaerulein - Another potent painkiller that reduces blood pressure and affects thermoregulation.
Adenoregulin - A 33 amino acid peptide that works with the adenosine receptor. This antibiotic peptide can have harm-reducing effects against many bacteria, fungi, and protozoa, including cancer cells.
Dermaseptin - Induces potent antimicrobial activity against bacteria, yeast, fungi, protozoa, and enveloped viruses that often cause severe opportunistic infections.
Tryptophyllins - Highly potent against the yeast candida, may have potential in cardiovascular, inflammatory and anticancer therapy.